Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects and best dose of palbociclib with cisplatin or
carboplatin in treating patients with solid tumors that have spread to other places and
usually cannot be cured or controlled with treatment. Palbociclib may stop the growth of
tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in
chemotherapy, such as cisplatin and carboplatin, work in different ways to stop the growth of
tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them
from spreading. Giving palbociclib with cisplatin or carboplatin may help stop tumor growth
in patients with advanced solid tumors.