Palonosetron Associated to Aprepitant in Prophylaxis of PONV

• Status: Unknown status
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The objective of this study is to investigate if aprepitant in association with palonosetron and dexamethasone could reduce the incidence of PONV in high-risk patients for this symptom, undergoing cancer surgery mastectomies.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto do Cancer do Estado de São Paulo
• Treatments: Aprepitant; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Fosaprepitant; Palonosetron

Criteria

Inclusion Criteria:

• patients submitted to breast cancer surgery

• non smokers

Exclusion Criteria:

• any contraindication to one of the drugs

• mental disease

• inability to understand the method or refusal to participate in the research