Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study first is designed to see what dose of indigo carmine ingested orally mixed with the standard colonoscopy prep is needed to provide adequate staining of the right colon. It then will use this adequate staining concentration of Indigo Carmine to study whether this dye will increase the detection of polyps during colonoscopy.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic

Criteria

Inclusion criteria:

• Patients presenting for screening or surveillance colonoscopy

• Must be aged 50 to 75 yrs

• Must be able and willing to sign informed consent

Exclusion criteria:

• Known Creatinine >1.2

• Cirrhosis

• Pregnancy or breast feeding

• History of anaphylaxis to any dye

• History of bowel surgery or small bowel obstruction

• History of aspiration

• History of dysphagia

• American Society of Anesthesia class >2

• History of abnormal liver function test in the last year

• History of any degree of cytopenia in the last year