Panobinostat (LBH589) in Patients With Metastatic Melanoma
Status:
Completed
Trial end date:
2017-03-13
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to determine the safety of LBH589 as well as to find
out what side effects it may cause and how effective it is against melanoma. LBH589 is a drug
which may slow down the growth of cancer cells or kill cancer cells by blocking certain
enzymes, which are proteins normally produced by cells. These enzymes are known to play an
important role in the development and reproduction of cancer cells. It is believed that
LBH589 works by helping to promote the activity of enzymes which turn on the mechanisms in
our cells that suppress cells from becoming cancerous.