Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients

• Status: Completed
• Trial end date: 2020-10-10
• Target enrollment: 0
• Participant gender: All

Summary

Periodic small volume boluses of diluted papaverine in peripheral arterial catheters of pediatric patients will prevent arterial spasm and help maintain patency of arterial catheters during general anesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston
• Treatments: Calcium heparin; Heparin; Papaverine

Criteria

Inclusion Criteria:

• All patients age 0-17 years who would require elective placements of arterial catheters based on patients clinical complexity (ex. congenital heart disease) or based on the type of surgery (ex. open heart surgery).

Exclusion Criteria:

• Patients with a history of significant liver dysfunction.

• Patients undergoing liver transplants.

• Patients with Grade 2 or more of intraventricular hemorrhage.

• All preterm patients with a gestational age less than 37 weeks at the time of surgery.