Parathyroidectomy vs Cinacalcet in the Treatment of Secondary Hyperparathyroidism Post Renal Transplantation

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The hypothesis of this study is that subtotal parathyroidectomy using minimally invasive surgery is superior to cinacalcet for the treatment of persistent secondary hyperparathyroidism (HPT) post renal transplant, with minimal morbidity and significantly reduces the cost of treatment post transplant.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Josep M Cruzado
• Treatments: Cinacalcet; Cinacalcet Hydrochloride

Criteria

Inclusion Criteria:

• Functioning renal transplant, GFR ≥ 30 ml / min

• Time post-transplant> 6 months

• PTHi>15pmol/L

• Calcium ≥2.63 mmol/L con phosphatemia ≤1.2 mmol/L

• Cervical scintigraphy

• Signed informed consent

Exclusion Criteria:

• Contraindication to surgery