Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic

• Status: Completed
• Trial end date: 2020-08-15
• Target enrollment: 0
• Participant gender: All

Summary

This study will be conducted to compare the efficacy and safety of Parecoxib versus Paracetamol for treatment of acute renal colic due to ureteric stones.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Collaborator: Amiri Hospital
• Treatments: Acetaminophen; Parecoxib

Criteria

Inclusion Criteria:

• Clinical signs and symptoms consistent with acute renal colic

Exclusion Criteria:

• Hypersensitivity to either Paracetamol or Parecoxib.

• History of peptic ulcer.

• Pregnant or breastfeeding females.

• Patients with hepatic impairment (Child-Pugh score >10).

• Patients with chronic kidney disease (CKD) Stage 4 or 5 (eGFR <30mls/min).

• History of coronary ischemia, peripheral vascular or cerebrovascular disease.