Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
Delayed anaemia has been reported in European travellers with malaria cured by artesunate.
Although no deaths related to this delayed anaemia have been reported so far, blood
transfusion has been necessary in some affected patients. Recent observations suggest that
this episodes of anaemia also occurs in endemic countries. The aim of this trial is to assess
the incidence of late onset anaemia after treatment with intravenous artesunate compared to
intravenous quinine, to identify patients at risk and to clarify the causes of this delayed
anaemia.