Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression

• Status: Completed
• Trial end date: 2005-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effectiveness of paroxetine versus interpersonal psychotherapy and a combination of the two in helping elderly patients with depression remain well and improve quality of their lives.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pittsburgh
• Treatments: Paroxetine

Criteria

Inclusion Criteria:

• Age 69 or older

• meets DSM-IV criteria for current unipolar major depression

• HRSD (17 item) score of 15 or higher

• Folstein Mini Mental Status exam score of 18 or higher

Exclusion Criteria:

• Lifetime diagnosis of any psychotic disorder or bipolar disorder

• alcohol or drug abuse within the past six months

• MATTIS Dementia Rating Score of 120 or less

• Contraindication to SSRI therapy

• Hyponatremia