RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as cyclophosphamide and doxorubicin, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving
radiation therapy together with cyclophosphamide and doxorubicin after surgery may kill any
tumor cells that remain.
PURPOSE: This phase I/II trial is studying the side effects of radiation therapy when given
together with cyclophosphamide and doxorubicin and to see how well they work in treating
women with stage I or stage II breast cancer who have undergone surgery.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins