Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
A patent foramen ovale (PFO) is found more frequently in patients with an ischemic stroke
than in control subjects.
Therapeutic options to prevent stroke recurrence include antiplatelet drugs, oral
anticoagulants, and transcatheter closure of the foramen. However, there are no published
studies showing convincingly the superiority of any one of these strategies in preventing
stroke recurrence.
The aim of this randomized clinical trial is to assess whether chronic anticoagulation on the
one hand and transcatheter on the other hand are superior to chronic antiplatelet therapy in
preventing stroke recurrence.
Phase:
Phase 3
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Treatments:
Anticoagulants Antivitamins K Apixaban Aspirin Clopidogrel Dabigatran Dipyridamole Rivaroxaban