Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty

• Status: Completed
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any impact on long term outcomes.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Golden Jubilee National Hospital
• Collaborator: Glasgow Caledonian University
• Treatments: Bupivacaine; Levobupivacaine; Polystyrene sulfonic acid; Ropivacaine

Criteria

Inclusion Criteria:

• All patients (age> 18years old) undergoing primary unilateral total knee arthroplasty (TKA) with a clinical diagnosis of osteoarthritis

Exclusion Criteria:

• Patients planned for uni-compartmental/bilateral or revision knee surgery patients

• Patients with a diagnosis of rheumatoid arthritis (RA)

• Patients with coagulation or anatomical defects e.g. preventing the use of spinal anaesthesia

• Known allergies to any medications within the trial

• Patients who were unable to give written informed consent

• Patients requiring pre-operative catheterisation for urinary outflow dysfunction

• Known neurological incident that would limit or make impossible early ambulation following surgery