Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma
Status:
Completed
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
This randomized pilot clinical trial studies pazopanib hydrochloride followed by chemotherapy
and surgery in treating patients with soft tissue sarcoma. Pazopanib hydrochloride may stop
the growth of tumor cells by blocking some of the enzymes that are needed for cell growth and
may also stop the growth of soft tissue sarcoma by blocking blood flow to the tumor. Giving
pazopanib hydrochloride and chemotherapy before surgery may make the tumor smaller and reduce
the amount of tissue that needs to be removed.