Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Serratus Anterior Plane Block (SAPB) in Cardiac Surgery

• Status: Not yet recruiting
• Trial end date: 2022-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if ultrasound-guided bilateral pectointercostal fascial plane blocks with unilateral serratus anterior plane block decrease pain scores, decrease opioid consumption, improve respiratory function, and improve quality of recovery in patients recovering from coronary artery bypass surgery (CABG) in comparison to pectointercostal fascial plane blocks alone.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical College of Wisconsin
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Subjects scheduled for cardiac surgery (CABG, CABG + single valve) involving primary median sternotomy and left-sided pleural chest tube

• Age 18-85 years of age

• BMI 18-50 kg/m2

• Weight > 60 kg

Exclusion Criteria:

• Left ventricular ejection fraction (LVEF) < 30%

• Preoperative, intraoperative, or immediate post-operative placement of intra-aortic balloon pump or deployment of extra-corporeal membrane oxygenation (ECMO)

• Inability to understand or speak English

• Allergy to bupivacaine or other amide local anesthetic

• Contraindication to peripheral nerve block (e.g. local infection, previous trauma to the block site)

• Chronic opioid consumption (daily oral morphine equivalent of >20 mg) in the past three months

• Severe pulmonary or hepatic disease

• Neurological deficit or disorder

• Suspected or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past two years

• Uncontrolled anxiety, schizophrenia, or other severe psychiatric disorder