Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes Trial
Status:
Withdrawn
Trial end date:
2023-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if the use of adjunctive catheter-directed
thrombolysis (CDT), which includes the intrathrombus administration of rt-PA
(Activase/Alteplase), can prevent post-thrombotic syndrome (PTS) in pediatric patients with
symptomatic proximal deep vein thrombosis (DVT) as compared with optimal standard
anticoagulation alone.
Phase:
Phase 3
Details
Lead Sponsor:
University of Colorado, Denver
Collaborators:
Genentech, Inc. Mid America Heart Institute National Heart, Lung, and Blood Institute (NHLBI) RTI International