Pelvic RT Versus Prophylactic Extended-field RT in Patients With Cervical Cancer
Status:
Recruiting
Trial end date:
2025-06-01
Target enrollment:
Participant gender:
Summary
To investigate the value of prophylactic extended-field irradiation (EFI), we conduct a
randomized clinical trial to compare the efficacy and toxicity of pelvic irradiation and
prophylactic EFI in selected patients with cervical cancer treated with definitive concurrent
chemoradiotherapy. External beam radiation therapy is delivered with intensity-modulated
radiation therapy (IMRT).
Phase:
Phase 3
Details
Lead Sponsor:
Peking Union Medical College Hospital
Collaborators:
Affiliated Cancer Hospital of Zhengzhou University Beijing Obstetrics and Gynecology Hospital Cancer Institute and Hospital, Chinese Academy of Medical Sciences Cangzhou Central Hospital China-Japan Union Hospital, Jilin University First Affiliated Hospital of Chongqing Medical University First Affiliated Hospital of Guangxi Medical University First Affiliated Hospital Xi'an Jiaotong University General Hospital of Benxi Iron & Steel Industry Group General Hospital of Ningxia Medical University Guizhou Provincial People's Hospital Harbin Medical University Third Affiliated Hospital Henan Provincial Hospital Henan Provincial People's Hospital Jiangsu Cancer Institute & Hospital Jilin Provincial Tumor Hospital Peking University First Hospital Second Affiliated Hospital of Xi'an Jiaotong University Second Hospital of Jilin University Seventh Medical Center of PLA Army General Hospital Shengjing Hospital Tangshan People's Hospital The 940th Hospital of Joint Logistics Support Force，PLA. The Affiliated Hospital of Inner Mongolia Medical University The Affiliated Tumor Hospital of Xinjiang Medical University The First Affiliated Hospital of Zhengzhou University The Second Affiliated Hospital of Dalian Medical University the Seventh Medical Center of PLA General Hospital Tumor Hospital of Gansu West China Second University Hospital Wuhan Union Hospital, China Xi'an Gaoxin Hospital Xi’an Gaoxin Hospital Xiangya Hospital of Central South University Zhejiang Cancer Hospital Zhongnan Hospital of Wuhan University & Second Clinical Hospital of Wuhan University