Overview

Pembrolizumab and GM-CSF in Biliary Cancer

Status:
Active, not recruiting
Trial end date:
2023-12-30
Target enrollment:
Participant gender:
Summary
This is an open label phase II trial to examine efficacy and safety of a novel combination of pembrolizumab plus induction GM-CSF in patients with advanced biliary cancers treated at University of California, San Francisco (UCSF). This phase II study will examine the efficacy and safety of the novel combination of pembrolizumab plus induction GM-CSF in advanced biliary cancer patients with the hypotheses that the combination may increase proportion of patients with overall response compared to contemporary historical controls, with acceptable safety.
Phase:
Phase 2
Details
Lead Sponsor:
Robin Kate Kelley
Collaborators:
American Society of Clinical Oncology
Merck Sharp & Dohme Corp.
Treatments:
Pembrolizumab
Sargramostim