Overview

Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma

Status:
Recruiting
Trial end date:
2026-05-31
Target enrollment:
Participant gender:
Summary
This is an open-label, single center, one cohort, non-randomized, phase I/II study. The aim is to evaluate the efficacy and safety of the combination of hypofractionated radiotherapy (HRT) and pembrolizumab on local tumor control in mucosal melanoma patients. Treatment effect will be compared with historical radiation therapy-alone control data.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Pembrolizumab