Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
Status:
Terminated
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes
needed for their growth. Drugs used in chemotherapy, such as gemcitabine, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Radiation therapy uses high energy x-rays to kill tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of pemetrexed when
given together with radiation therapy in treating patients with locally advanced pancreatic
cancer.
Phase:
Phase 1
Details
Lead Sponsor:
Comprehensive Cancer Center of Wake Forest University Wake Forest University Health Sciences