Pemetrexed Plus Gemcitabine in Metastatic Breast Cancer Patients After Receiving Taxane Therapy

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine if the two drugs can help patients feel better while causing the tumor to become smaller or disappear; evaluate the safety of giving both pemetrexed and gemcitabine in patients with advanced breast cancer.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eli Lilly and Company
• Treatments: Gemcitabine; Pemetrexed; Taxane

Criteria

Inclusion Criteria:

• Must have received prior chemotherapy with Taxol (paclitaxel) or Taxotere (docetaxel).

• Less than 3 different chemotherapy treatments for metastatic disease.

• Prior treatment with hormonal and/or radiation therapy.

• Must have disease that can be measured.

• Must be able to take care of self needs for example personal hygiene

Exclusion Criteria:

• Must not be pregnant or breast-feeding.

• Cancer that has spread to the brain.

• Treatment with Gemcitabine or Pemetrexed

• Unable to take folic acid or Vitamin B12

• Treatment for another cancer within the last 5 years