Pemetrexed and Cisplatin Treatment Before Surgery in Non Small Cell Lung Cancer

• Status: Terminated
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine the response to this regimen for therapy prior surgery in patients with locally advanced disease or metastatic disease.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eli Lilly and Company
• Treatments: Cisplatin; Pemetrexed

Criteria

Inclusion Criteria:

• Diagnosis of non-small-cell carcinoma of the lung

• Patients with locally advanced disease or metastatic disease, candidates to surgery after evaluation by oncologist and thoracic surgeon

• Tumour with possibility of curative surgery

• At least one uni-dimensionally measurable lesion

• Adequate pulmonary function to perform the planned surgical resection

Exclusion Criteria:

• Active infection (at the investigator's discretion)

• Pregnancy or breast-feeding

• Serious concomitant illness at the investigator's discretion

• Previous diagnosis of malignant disease

• They have received treatment during the last 30 days with a drug, other than the study drug, that has not received regulatory approval for any indication at the time of their entry in the study