Perampanel for Treatment of Adults With Refractory Focal Epilepsy : a Pilot Study.
Status:
Terminated
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
The goal of the present study is to evaluate ("screen") a large number (12) of different dual
therapies of perampanel + another AED ("PMP+") for a large, 75-100% seizure frequency
reduction. The design of the study will differ from usual AED studies. The study will be (i)
open label, with (ii) a small n per group, n=6, with (iii) outcome measures a 'blockbuster
effect': (a) ≥75 seizure frequency reduction; and (b) seizure freedom.