Perineural Steroids for Peripheral Nerve Blocks

• Status: Completed
• Trial end date: 2017-08-31
• Target enrollment: 0
• Participant gender: All

Summary

This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wake Forest University Health Sciences
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• elective robotic medial MAKO partial knee arthroplasty

• agreed to a regional anesthesia technique

Exclusion Criteria:

• contraindications to regional anesthesia

• presence of a progressive neurological deficit

• a pre-existing coagulopathy, infection

• insulin and non-insulin dependent diabetes mellitus

• systemic use of corticosteroids within 30 days of surgery

• chronic use of an opioid analgesic (>3 months or a combined total of more than 40 mg Oxycodone equivalents a day)

• pregnancy

• a prior history of an adverse event (for example: psychosis) or an allergy to dexamethasone