Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Periodontal disease (commonly called gum disease) is generally treated by deep cleaning of the root surfaces of the teeth. This is also called scaling and root planing. Placing a topical antibiotic into the periodontal pocket at the time of scaling and root planing may help reduce pocket depth and thus help the periodontal disease. Periocline (minocycline HCl) 2.1% gel is a topical antibiotic approved in a number of countries for this use, and is now being tested in the US.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sunstar Americas
• Treatments: Minocycline

Criteria

Inclusion Criteria:

• moderate to severe periodontitis

Exclusion Criteria:

• recent periodontal therapy

• certain medical or dental conditions

• pregnancy

• allergy to active drug or related drugs