Periodontal Therapy in Thalassemia Major Patients

• Status: Completed
• Trial end date: 2017-06-16
• Target enrollment: 0
• Participant gender: All

Summary

The study aims to evaluate the effect of local non surgical periodontal therapy on the systemic pro-inflammatory markers in the β-thalassemia (TM-β) patients with chronic periodontitis and systemically healthy demographically matched controls with chronic periodontitis. Both groups will receive non surgical periodontal therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: King Saud University

Criteria

Inclusion Criteria:

1. Written and verbal consent

2. (TM-β) patients with gingivitis

3. Age: ≥10 years

4. Patients who have received or are receiving iron chelation therapy with deferasirox, calcium, vitamin D, and regular erythrocyte transfusion.

Exclusion Criteria:

1. Presence of hepatitis B or C or HIV-AIDS (Human immunodeficiency Virus- Acquired immunodeficiency syndrome).

2. Presence of any other known systemic disease.

3. Use of antibiotics or anti-inflammatory drugs within the past 6 months.

4. Dental prophylaxes in the last 6 months