Overview

Perioperative Chemotherapy Compared To Neoadjuvant Chemoradiation in Patients With Adenocarcinoma of the Esophagus

Status:
Active, not recruiting

Trial end date:
2024-06-01

Target enrollment:

Participant gender:

Summary

The trial is designed to investigate differences in outcome of patients with esophageal adenocarcinoma and junctional adenocarcinoma treated with perioperative (neoadjuvant + adjuvant) chemotherapy (FLOT) plus surgical resection versus neoadjuvant chemoradiation (CROSS) plus surgical resection.

Phase:

Phase 3

Details

Lead Sponsor:

University Hospital Freiburg

Collaborators:

Clinical Trials Unit Freiburg
CTC laboratories at University of Hamburg and University of Freiburg
ESOPEC reference pathology at the University of Freiburg
Universitätsklinikum Leipzig, Universitäres Krebszentrum (UCCL)

Treatments:

Carboplatin
Docetaxel
Fluorouracil
Leucovorin
Oxaliplatin
Paclitaxel