Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures. The investigators hypothesize that patients who receive GC will have improved ROM and functional outcome measures compared to patients who do not receive GC. In addition, this study aims to determine if there is a difference in rates of complications and postoperative pain control between the GC and non-GC groups. In order to accomplish these aims, the investigators will conduct a prospective, randomized, controlled investigation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: C. Liam Dwyer
• Treatments: Dexamethasone; Glucocorticoids; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Patient 18 years of age and older.

• Patients undergoing ORIF with VP fixation of an acute, isolated DRF with or without associated distal ulna fracture and with or without associated carpal tunnel release

Exclusion Criteria:

• Worker's compensation patient

• Non-operatively treated fractures

• Open fractures

• Preoperative neurovascular injury

• Coexisting fractures or injuries

• Diabetes mellitus

• Allergy or contraindication to GCs

• Associated non-orthopedic injury that would prohibit the administration of GCs

• Patients currently incarcerated

• Pregnant patients