Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Acute pain management following major surgical procedures in pediatric patients continues to
be a challenge, especially after extensive posterior spine fusions.
Spine surgery is particularly traumatic, initiating pain in both peripheral and central
pathways. While the standard management of post-surgical pain involves a multimodal approach,
opioids provide the predominant benefit. However, opioid use is associated with many adverse
effects, including nausea, constipation, and pruritus. Perioperative methadone may decrease
total opioid consumption and adverse effects as well as improve satisfaction with pain
management after scoliosis repair.