Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO
Status:
Completed
Trial end date:
2018-02-06
Target enrollment:
Participant gender:
Summary
This interventional study will evaluate the retinal vascular dynamics associated with
Intravitreal Aflibercept Injection (IAI) therapy in eyes with diabetic macular edema (DME) or
macular edema secondary to retinal vein occlusion (RVO). Ultra-widefield fluorescein
angiography and optical coherence tomography (OCT) angiography will be performed at multiple
timepoints to assess the changes in retinal vascular leakage, ischemia, and vascular
abnormalities throughout the study duration and compare these alterations to baseline.