Peroperative Administration of Tranexamic Acid in Roux-en-Y Gastric Bypass and One-anastomosis Gastric Bypass

• Status: Not yet recruiting
• Trial end date: 2025-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The incidence of bleeding after metabolic surgery seems to increase. The administration of a drug (tranexamic acid) that can reduce bleeding could possibly also reduce bleeding after metabolic surgery.

Objective: This study aims to determine whether administration of tranexamic acid before surgery can reduce postoperative bleeding in patients undergoing gastric bypass.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Franciscus Gasthuis
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Primary metabolic procedure;

• Gastric bypass: Roux-en-Y gastric bypass or One-anastomoses gastric bypass;

• ≥18 years;

• Good command of the Dutch or English language.

Exclusion Criteria:

• Patients unwilling to give informed consent;

• Patients with a medical history of bleeding or VTE (defined as, pulmonary embolism (PE) or deep vein thrombosis (DVT));

• Patients who use anticoagulants;

• Arterial bleeding or (iatrogenic) bleeding during the procedure coming from surrounding organs or vascular structures such as the liver or the spleen.