Personalized Treatment Algorithms for Difficult-to-treat Asthma
Status:
Completed
Trial end date:
2019-10-03
Target enrollment:
Participant gender:
Summary
Asthma is a common, complex and costly chronic condition. Moreover, asthma is heterogeneous
in terms of treatment response. This heterogeneity contributes to the difficulty in both
studying and treating asthma. This is a pilot study to improve health outcomes in youths with
difficult to treat asthma with ongoing symptoms and healthcare utilization despite medium to
high doses of inhaled corticosteroids. Asthma heterogeneity in both disease pathophysiology
and treatment response contributes to the difficulty in both studying and managing asthma. In
order to begin to develop personalized algorithms for patients, investigators need to model
novel biomarkers and other factors that contribute to individual differences in asthma
outcome and test other factors that contribute to individual differences in asthma outcome
and test personalized treatment strategies.