Pethidine Versus Nitrous Oxide for Pain Relief During Labor

• Status: Recruiting
• Trial end date: 2020-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

Systematic opioids and inhaled nitrous oxide (N2O ) are common methods for pain relief during labor. The aim of the current study is to evaluate the efficacy of systemic pethidine compared to N2O given for pain relieve in term, multiparous women in labor.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: HaEmek Medical Center, Israel
• Treatments: Meperidine; Nitrous Oxide

Criteria

Inclusion Criteria:

1. Multiparity (para 2 or more).

2. Term pregnancy: 37-42 weeks of gestation.

3. Singleton pregnancy.

4. Vertex presentation.

5. In labor: at least 2 contraction in ten minutes and cervical dilatation of 2 centimeters or more.

Exclusion Criteria:

1. Women who desire epidural as a first line analgesia during labor.

2. Women receiving pethidine during the last 24 hours (prior to entering labor room).

3. Contra-indication for vaginal delivery.

4. Contra-indication or allergic reaction to either pethidine or nitrous oxide.

5. History of drug abuse.

6. Previous cesarean delivery.