Overview

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

Status:
Active, not recruiting
Trial end date:
2021-12-05
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects and best dose of pevonedistat when given together with decitabine in treating patients with high risk acute myeloid leukemia. Pevonedistat and decitabine may stop the growth of cancer cells by blocking some of the enzymes need for cell growth.
Phase:
Phase 1
Details
Lead Sponsor:
City of Hope Medical Center
Collaborator:
National Cancer Institute (NCI)
Treatments:
Azacitidine
Decitabine
Enzyme Inhibitors
Pevonedistat