Ph1 Marinol Interaction Study - Part 1 - 1

• Status: Terminated
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the effects of oral dronabinol tetrahydrocannabinol (THC) on withdrawal symptoms in marijuana dependent volunteers, and evaluate the safety, pharmacokinetics (PK), and cardiovascular effects of the combination of oral dronabinol and smoked marijuana to determine if there are potential significant interactions before conducting outpatient studies.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Dronabinol

Criteria

Inclusion Criteria:

• Must be between the ages of 18 to 45 years of age

• Must be in good general health

• Must meet DSM-IV criteria for marijuana dependence and are non- treatment seekers at the time of study

• Must be able to provide written informed consent

• Must be able to provide 1 marijuana positive urine specimen (> 50 ng/mL) within the 28-day screening period

• If female and of child bearing potential, must agree to use birth control.

Exclusion

Criteria:

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