Overview

Pharmaco-metabolomic Effects of Statins: METASTATINE

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Statins are effective in cardio-vascular prevention by lowering LDL-Cholesterol levels but also through other mechanisms poorly understood. Our hypothesis is that some of these effects are mediated by microbiota alteration, leading to diminution of expression of microbiota derived pro-atherogenic metabolites.
Phase:
Phase 3
Details
Lead Sponsor:
French Cardiology Society
Collaborators:
Fédération francaise de cardiologie
Fondation Coeur et Recherche
ICAN Nutrition Education and Research
Treatments:
Atorvastatin
Atorvastatin Calcium
Hydroxymethylglutaryl-CoA Reductase Inhibitors