Pharmacodynamic Differences Between Branded and Unbranded Remifentanil Molecules

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Unbranded drug molecules are produced after the patent of a given drug has expired. Unbranded molecules of Remifentanil have been marketed in Colombia, and several reports by anesthesiologist indicate that there are differences in the physiologic response of patients to these molecules. The investigators hypothesized that unbranded molecules of remifentanil require higher doses to obtain desired physiological responses as compared to the branded molecule.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fundación Universitaria de Ciencias de la Salud
• Collaborator: Hospital de San Jose
• Treatments: Remifentanil

Criteria

Inclusion Criteria:

• Patients requiring orotracheal intubation

• 18-50 years old

• Body mass index <31 kg/m2

• Written informed consent

Exclusion Criteria:

• Pregnancy

• Risk of difficult airway

• History of opioid use