Pharmacogenomic Evaluation of Antihypertensive Responses
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
There are many medications available for the treatment of high blood pressure (hypertension),
but finding the right one for a specific patient can be challenging. In fact, it is estimated
that only 34% of people with hypertension have their blood pressure under control. The
hypothesis is that genetic differences between individuals influence their response to
antihypertensive medications. This study is aimed at determining the genetic factors that may
influence a person's response to either a beta-blocker or a thiazide diuretic. The hope is
that through this research, we may someday be able to use an individual's genetic information
to guide the selection of their blood pressure medicine, leading to better control of blood
pressure, and less need for the current trial and error process.