Pharmacokinetic (PK)Research on Chinese Children of Hemophilia

• Status: Unknown status
• Trial end date: 2021-08-30
• Target enrollment: 0
• Participant gender: Male

Summary

The study start on June 30, 2018. The Severe(F Ⅷ<1%) hemophilia A children without F Ⅷ inhibitor combining were recruited to Test the concentration of the drug in the blood to provide better treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Children's Hospital

Criteria

Inclusion Criteria:

• FⅧ<1% ,

• 1-14years old,

• There have been at least one history of bleeding in any joint of the knee, elbow, or ankle.

• A blood product containing FVIII is applied.

• There were no inhibitors at the time of enrollment, and there was no inhibitor-positive history and family history.

• Clinical visits are available on a regular basis and data is available, and preventive treatment is available prior to enrollment.

• The child was enrolled in the group and the guardian agreed.

Exclusion Criteria:

• Combining other disease researchers believes that it is not suitable for enrollment.

• FVIII inhibitor was found.

• Refuse to participate in research