Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment
Status:
Completed
Trial end date:
2021-10-18
Target enrollment:
Participant gender:
Summary
This Phase 1 study is being conducted to evaluate the effect of severe renal impairment on
the PK, safety and tolerability of Aztreonam-Avibactam. Results from this study along with
previous renal impairment data from each of the Aztreonam-Avibactam components will be used
to confirm the proposed dosing adjustment in severe renal impairment which was based on
modelling/simulation.