Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction
Status:
Completed
Trial end date:
2007-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see how vincristine, when placed in an oil droplet called a
liposome (VSLI), is absorbed, distributed (moved around) and excreted from the the body
(pharmacokinetics). This study will also assess the safety of VSLI and to see if VSLI will
slow the growth or shrink tumors in patients with metastatic melanoma that has resulted in
liver impairment, and who have relapsed after previous therapies.