Overview
Pharmacokinetics and Drug Interaction Study Between Amlodipine,Olmesartan and Rosuvastatin in Healthy Adult Volunteers
Status:
Completed
Completed
Trial end date:
2014-06-01
2014-06-01
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
The purpose of this study is to evaluate the pharmacokinetics profile and drug-drug interaction between amlodipine, olmesartan and rosuvastatin in healthy adult volunteers.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Daewoong Pharmaceutical Co. LTD.Treatments:
Olmesartan
Olmesartan Medoxomil
Rosuvastatin Calcium
Criteria
Inclusion Criteria:- Healthy male subjects aged 19 - 55 years
- A body mass index in the range 19 - 27 kg/m2
- Willingness to participate during the entire study period
- Written informed consent after being fully informed about the study procedures
Exclusion Criteria:
- Any past medical history of hepatic, renal, gastrointestinal, respiratory, endocrine,
psychiatric, neurologic, haemato-oncologic or cardiovascular disease
- History of clinically significant drug hypersensitivity
- Use of medication within 7 days before the first dose
- Heavy drinker (>140 g/week)
- Whole blood donation during 60 days before the study
- Judged not eligible for study participation by investigator