Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
This is a Phase 4, multicenter, open-label study designed to characterize the pharmacokinetic
(PK) profile of total bupivacaine in approximately 15 adult subjects undergoing primary
unilateral total knee arthroplasty (TKA) with bupivacaine hydrochloride (HCl) spinal nerve
block (SNB) and EXPAREL local infiltration into the surgical site.