Pharmacokinetics and Safety of Intravenous Topiramate in Adult Patients

• Status: Completed
• Trial end date: 2010-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The aims of this study are to determine, in adult patients on maintenance topiramate therapy, the steady-state pharmacokinetics and safety of orally and intravenously administered topiramate.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Minnesota; University of Minnesota - Clinical and Translational Science Institute
• Treatments: Topiramate

Criteria

Inclusion Criteria:

• Persons taking topiramate

• Persons 18 years of age and older

Exclusion Criteria:

• Patients who are pregnant

• Patients who are breast feeding

• Patients with significant medical problems who may not tolerate intravenous administration

• Patients taking medications known to affect topiramate disposition