Pharmacokinetics of Antiepileptics in Patients on CRRT
Status:
Completed
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
The purpose of the study is to measure levels of any of the following AEDs (levetiracetam,
phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on
critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and
optimize dosing strategies in patients on CRRT.
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore
Collaborator:
Center for Translational Medicine (CTM), University of Maryland School of Pharmacy