Pharmacokinetics of Apixaban in Patients With Short Bowel Syndrome Requiring Long Term Parenteral Nutrition
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Short bowel syndrome (SBS) is defined as a loss of function of the small intestine resulting
in a malabsorptive disorder. In SBS, oral drug absorption may be altered due to extensive
intestinal resection. It remains unclear to what extent apixaban exposure is impacted in
SBS.Therefore this study tries to investigate the pharmacokinetics (PK) of apixaban in adult
patients with SBS requiring long-term parenteral nutrition (PN).