Pharmacokinetics of Multiple Dose Methadone in Children Treated for Opiate Withdrawal
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to learn more about how the study drug, methadone, prescribed by
an infant's or child's physician as part of standard medical care, is processed in children
and young adults. While this drug is used extensively in infants and children, it has not
been extensively studied in this population.
Physicians do not have very much information on how long it takes for methadone to be removed
from the blood circulation and passed out of the body. Physicians need more information to
guide how much and how often we should give methadone to children/young adults to ensure they
get the maximum effect with the minimum amount of drug. During this research study, the study
team will collect information about how this drug is processed in infants and children.
Details
Lead Sponsor:
Kevin Watt Phillip Brian Smith
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)