Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment
Status:
Not yet recruiting
Trial end date:
2021-05-01
Target enrollment:
Participant gender:
Summary
There are currently no approved therapies for patients with coronavirus disease (COVID-19)
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infusion of ascorbic
acid (vitamin C) has been shown to increase activity of lymphocytes, which are a crucial
component of the body's defense against viral disease progression and adaptive immunity.
Ascorbic acid infusion has been shown to be a safe treatment for patients suffering from
sepsis and certain types of cancer. This study is designed to evaluate the safety and
efficacy of ascorbic acid in the form of sequential I.V. infusions (Ascor®) for patients with
suspected COVID-19 who are unlikely to require mechanical ventilation within 24 hours of
study intervention.