Pharmacologic Study of Oseltamivir in Healthy Volunteers
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
"Pharmacologic Study of Oseltamivir in Healthy Volunteers" is a Phase I study in which 8 to
32 adult healthy Thai volunteers will be randomized to one of four drug doses and regimens
within each of 4 visits. The study is being conducted at the Bangkok Hospital of Tropical
Diseases Research Unit, Faculty of Tropical Medicine, and commenced enrolling healthy
volunteers on 23 November 2006. The duration of the study is expected to be approximately
four months. The goals of this study are to assess the use of loading dose oseltamivir and
the concomitant use of probenecid and to characterize the pharmacokinetic properties of
oseltamivir in Thai subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Mahidol University
Collaborators:
National Institute of Allergy and Infectious Diseases (NIAID) Southeast Asia Influenza Clinical Research Network