Pharmacologic Treatment of PTSD in Sexually Abused Children

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the benefit of adding sertraline (Zoloft®) to Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for sexually abused children who have Posttraumatic Stress Disorder (PTSD).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Allegheny Singer Research Institute; Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Sertraline

Criteria

Inclusion:

1. Ages 10-17 years, inclusive

2. Confirmed sexual abuse

3. At least 5 PTSD symptoms on KSADS-PL, with at least one symptom in each of 3 symptom clusters (reexperiencing, avoidance, arousal)

4. Parent/primary caregiver available to participate in treatment

5. Assent with parental consent to participate

Exclusion:

1. Non-English speaking

2. schizophrenia or other severe psychotic disorder

3. MR (IQ<60) or PDD preventing CBT treatment

4. taking current psychotropic medication

5. documented substance dependence (substance abuse allowed)