Pharmacological Management of Delirium

• Status: Completed
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to develop and test the feasibility of using a specific pharmacological protocol to reduce delirium burden among older adults in the Intensive Care Unit (ICU). The study will test the efficacy of a pharmacological intervention in reducing delirium severity and duration as well as length of stay and mortality compared to usual care.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University
• Collaborator: National Institute on Aging (NIA)
• Treatments: Cholinergic Antagonists; Haloperidol; Haloperidol decanoate

Criteria

Inclusion Criteria:

• 18 years of age or older

• Hospitalized on an ICU ward

• Delirium based on the RASS and the CAM-ICU assessments at any day during ICU stay

• English speaking

Exclusion Criteria:

• Admitted directly to a regular non-ICU ward

• Previously enrolled in the study

• Not eligible for delirium assessment as determined by RASS scores

• Prior history of severe mental illness

• Alcohol-related delirium

• Pregnant or nursing

• Have had an aphasic stroke